Government of Canada / Gouvernement du Canada
Symbol of the Government of Canada

Search

Narcotic Control Regulations (C.R.C., c. 1041)

Regulations are current to 2024-08-18 and last amended on 2024-06-05. Previous Versions

SCHEDULE(Section 2)

  • 1 
    Opium Poppy (Papaver somniferum), its preparations, derivatives, alkaloids and salts, including:
    • (1) 
      Opium
    • (2) 
      Codeine (methylmorphine)
    • (3) 
      Morphine (7,8-didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol)
    • (4) 
      Thebaine (paramorphine)
    • and the salts, derivatives and salts of derivatives of the substances set out in subitems (1) to (4), including:
    • (5) 
      Acetorphine (acetyletorphine)
    • (6) 
      Acetyldihydrocodeine (4,5-epoxy-3-methoxy-17-methylmorphinan-6-ol acetate)
    • (7) 
      Benzylmorphine (7,8-didehydro-4,5-epoxy-17-methyl-3-(phenylmethoxy) morphinan-6-ol)
    • (8) 
      Codoxime (dihydrocodeinone O-(carboxymethyl)oxime)
    • (9) 
      Desomorphine (dihydrodeoxymorphine)
    • (10) 
      Diacetylmorphine (heroin)
    • (11) 
      Dihydrocodeine (4,5-epoxy-3-methoxy-17-methylmorphinan-6-ol)
    • (12) 
      Dihydromorphine (4,5-epoxy-17-methylmorphinan-3,6-diol)
    • (13) 
      Ethylmorphine (7,8-didehydro-4,5-epoxy-3-ethoxy-17-methylmorphinan-6-ol)
    • (14) 
      Etorphine (tetrahydro-7α-(1-hydroxy-1-methylbutyl)-6,14-endo-ethenooripavine)
    • (15) 
      Hydrocodone (dihydrocodeinone)
    • (16) 
      Hydromorphinol (dihydro-14-hydroxymorphine)
    • (17) 
      Hydromorphone (dihydromorphinone)
    • (18) 
      Methyldesorphine (Δ6-deoxy-6-methylmorphine)
    • (19) 
      Methyldihydromorphine (dihydro-6-methylmorphine)
    • (20) 
      Metopon (dihydromethylmorphinone)
    • (21) 
      Morphine-N-oxide (morphine oxide)
    • (22) 
      Myrophine (benzylmorphine myristate)
    • (23) 
      Nalorphine (N-allylnormorphine)
    • (24) 
      Nicocodine (6-nicotinylcodeine)
    • (25) 
      Nicomorphine (dinicotinylmorphine)
    • (26) 
      Norcodeine (N-desmethylcodeine)
    • (27) 
      Normorphine (N-desmethylmorphine)
    • (28) 
      Oxycodone (dihydrohydroxycodeinone)
    • (29) 
      Oxymorphone (dihydrohydroxymorphinone)
    • (30) 
      Pholcodine (3-[2-(4-morpholinyl)ethyl]morphine)
    • (31) 
      Thebacon (acetyldihydrocodeinone)
    • but not including
    • (32) 
      Apomorphine (5,6,6a,7-tetrahydro-6-methyl-4H-dibenzo[de,g]quinoline-10,11-diol) and its salts
    • (33) 
      Cyprenorphine (N-(cyclopropylmethyl)-6,7,8,14-tetrahydro-7α-(1-hydroxy-1-methylethyl)-6,14-endo-ethenonororipavine) and its salts
    • (33.1) 
      [Repealed, SOR/2016-239, s. 8]
    • (34) 
      Nalmefene (17-(cyclopropylmethyl)-4,5α-epoxy-6-methylenemorphinan-3,14-diol) and its salts
    • (34.1) 
      Naloxone (4,5α-epoxy-3,14-dihydroxy-17-(2-propenyl)morphinan-6-one) and its salts
    • (34.2) 
      Naltrexone (17-(cyclopropylmethyl)-4,5α-epoxy-3,14-dihydroxymorphinan-6-one) and its salts
    • (34.3) 
      Methylnaltrexone (17-(cyclopropylmethyl)-4,5α-epoxy-3,14-dihydroxy-17-methyl-6-oxomorphinanium) and its salts
    • (34.4) 
      Naloxegol (4,5α-epoxy-6α-(3,6,9,12,15,18,21-heptaoxadocos-1-yloxy)-17-(2-propenyl)morphinan-3,14-diol) and its salts
    • (35) 
      Narcotine (6,7-dimethoxy-3-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo [4,5-g]isoquinolin-5-yl)-1(3H)-isobenzofuranone) and its salts
    • (36) 
      Papaverine (1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxyisoquinoline) and its salts
    • (37) 
      Poppy seed
  • 2 
    Coca (Erythroxylum), its preparations, derivatives, alkaloids and salts, including:
    • (1) 
      Coca leaves
    • (2) 
      Cocaine (benzoylmethylecgonine)
    • (3) 
      Ecgonine (3-hydroxy-2-tropane carboxylic acid)
    • but not including
    • (4) 
      123l-ioflupane
  • 3 
    Phenylpiperidines, their intermediates, salts, derivatives and analogues and salts of intermediates, derivatives and analogues, including:
    • (1) 
      Allylprodine (3-allyl-1-methyl-4-phenyl-4-piperidinol propionate)
    • (2) 
      Alphameprodine (α-3-ethyl-1-methyl-4-phenyl-4-piperidinol propionate)
    • (3) 
      Alphaprodine (α-1,3-dimethyl-4-phenyl-4-piperidinol propionate)
    • (4) 
      Anileridine (ethyl 1-[2-(p-aminophenyl) ethyl]-4-phenylpiperidine-4-carboxylate)
    • (5) 
      Betameprodine (ß-3-ethyl-1-methyl-4-phenyl-4-piperidinol propionate)
    • (6) 
      Betaprodine (ß-1,3-dimethyl-4-phenyl-4-piperidinol propionate)
    • (7) 
      Benzethidine (ethyl 1-(2-benzyloxyethyl)-4-phenylpiperidine-4-carboxylate)
    • (8) 
      Diphenoxylate (ethyl 1-(3-cyano-3,3-diphenylpropyl)-4-phenylpiperidine-4-carboxylate)
    • (9) 
      Difenoxin (1-(3-cyano-3,3-diphenylpropyl)-4-phenylpiperidine-4-carboxylate)
    • (10) 
      Etoxeridine (ethyl 1-[2-(2-hydroxyethoxy) ethyl]- 4-phenylpiperidine-4-carboxylate)
    • (11) 
      Furethidine (ethyl 1-(2-tetrahydrofurfuryloxyethyl)- 4-phenylpiperidine-4-carboxylate)
    • (12) 
      Hydroxypethidine (ethyl 4-(m-hydroxyphenyl)-1-methylpiperidine-4-carboxylate)
    • (13) 
      Ketobemidone (1-[4-(m-hydroxyphenyl)-1-methyl-4-piperidyl]-1-propanone)
    • (14) 
      Methylphenylisonipecotonitrile (4-cyano-1-methyl-4-phenylpiperidine)
    • (15) 
      Morpheridine (ethyl 1-(2-morpholinoethyl)-4- phenylpiperidine-4-carboxylate)
    • (16) 
      Norpethidine (ethyl 4-phenylpiperidine-4-carboxylate)
    • (17) 
      Pethidine (ethyl 1-methyl-4-phenylpiperidine-4-carboxylate)
    • (18) 
      Phenoperidine (ethyl 1-(3-hydroxy-3-phenylpropyl)-4-phenylpiperidine-4-carboxylate)
    • (19) 
      Piminodine (ethyl 1-[3-(phenylamino)propyl]-4-phenylpiperidine-4-carboxylate)
    • (20) 
      Properidine (isopropyl 1-methyl-4-phenylpiperidine-4- carboxylate)
    • (21) 
      Trimeperidine (1,2,5-trimethyl-4-phenyl-4-piperidinol propionate)
    • (22) 
      Pethidine Intermediate C (1-methyl-4-phenylpiperidine-4-carboxylate)
    • but not including
    • (23) 
      Carperidine (ethyl 1-(2-carbamylethyl)-4-phenylpiperidine-4-carboxylate) and its salts
    • (24) 
      Oxpheneridine (ethyl 1-(2-hydroxy-2-phenylethyl)-4-phenylpiperidine-4-carboxylate) and its salts
  • 4 
    Phenazepines, their salts, derivatives and salts of derivatives including:
    • (1) 
      Proheptazine (hexahydro-1,3-dimethyl-4-phenyl-1Hazepin-4-ol propionate)
    • but not including
    • (2) 
      Ethoheptazine (ethyl hexahydro-1-methyl-4-phenylazepine-4-carboxylate) and its salts
    • (3) 
      Metethoheptazine (ethyl hexahydro-1,3-dimethyl-4-phenylazepine-4-carboxylate) and its salts
    • (4) 
      Metheptazine (methylhexahydro-1,2-dimethyl-4-phenylazepine-4-carboxylate) and its salts
  • 5 
    Amidones, their intermediates, salts, derivatives and salts of intermediates and derivatives, including:
    • (1) 
      Dimethylaminodiphenylbutanonitrile (4-cyano-2-dimethylamino-4,4-diphenylbutane)
    • (2) 
      Dipipanone (4,4-diphenyl-6-piperidino-3-heptanone)
    • (3) 
      Isomethadone (6-dimethylamino-5-methyl-4,4-diphenyl-3-hexanone)
    • (4) 
      Methadone (6-dimethylamino-4,4-diphenyl-3-heptanone)
    • (5) 
      Normethadone (6-dimethylamino-4,4-diphenyl-3-hexanone)
    • (6) 
      Norpipanone (4,4-diphenyl-6-piperidino-3-hexanone)
    • (7) 
      Phenadoxone (6-morpholino-4,4-diphenyl-3-heptanone)
  • 6 
    Methadols, their salts, derivatives and salts of derivatives, including:
    • (1) 
      Acetylmethadol (6-dimethylamino-4,4-diphenyl-3-heptanol acetate)
    • (2) 
      Alphacetylmethadol (α-6-dimethylamino-4,4-diphenyl-3-heptanol acetate)
    • (3) 
      Alphamethadol (α-6-dimethylamino-4,4-diphenyl-3-heptanol)
    • (4) 
      Betacetylmethadol (ß-6-dimethylamino-4,4-diphenyl-3-heptanol acetate)
    • (5) 
      Betamethadol (ß-6-dimethylamino-4,4-diphenyl-3-heptanol)
    • (6) 
      Dimepheptanol (6-dimethylamino-4,4-diphenyl-3-heptanol)
    • (7) 
      Noracymethadol (α-6-methylamino-4,4-diphenyl-3-heptanol acetate)
  • 7 
    Phenalkoxams, their salts, derivatives and salts of derivatives, including
    • (1) 
      Dimenoxadol (dimethylaminoethyl 1-ethoxy-1,1-diphenylacetate)
    • (2) 
      Dioxaphetyl butyrate (ethyl 2,2-diphenyl-4-morpholinobutyrate)
    • (3) 
      Dextropropoxyphene ([S-(R*,S*)]-α-[2-(dimethylamino)-1-methylethyl]-α-phenylbenzeneethanol, propanoate ester)
  • 8 
    Thiambutenes, their salts, derivatives and salts of derivatives, including:
    • (1) 
      Diethylthiambutene (N,N-diethyl-1-methyl-3,3-di-2-thienylallylamine)
    • (2) 
      Dimethylthiambutene (N,N,1-trimethyl-3,3-di-2-thienylallylamine)
    • (3) 
      Ethylmethylthiambutene (N-ethyl-N,1-dimethyl-3,3-di-2-thienylallylamine)
  • 9 
    Moramides, their intermediates, salts, derivatives and salts of intermediates and derivatives, including:
    • (1) 
      Dextromoramide (d-1-(3-methyl-4-morpholino-2,2-diphenylbutyryl)pyrrolidine)
    • (2) 
      Diphenylmorpholinoisovaleric acid (2-methyl-3-morpholino-1,1-diphenylpropionic acid)
    • (3) 
      Levomoramide (l-1-(3-methyl-4-morpholino-2,2-diphenylbutyryl)pyrrolidine)
    • (4) 
      Racemoramide (d,l-1-(3-methyl-4-morpholino-2,2- diphenylbutyryl)pyrrolidine)
  • 10 
    Morphinans, their salts, derivatives and salts of derivatives, including:
    • (1) 
      Buprenorphine (17-(cyclopropylmethyl)-α-(1,1-dimethylethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-α-methyl-6,14-ethenomorphinan-7-methanol)
    • (2) 
      Drotebanol (6ß,14-dihydroxy-3,4-dimethoxy-17-methylmorphinan)
    • (3) 
      Levomethorphan (1-3-methoxy-17-methylmorphinan)
    • (4) 
      Levorphanol (1-3-hydroxy-17-methylmorphinan)
    • (5) 
      Levophenacylmorphan (1-3-hydroxy-17-phenacylmorphinan)
    • (6) 
      Norlevorphanol (1-3-hydroxymorphinan)
    • (7) 
      Phenomorphan (3-hydroxy-17-(2-phenylethyl)morphinan)
    • (8) 
      Racemethorphan (d,1-3-methoxy-17-methylmorphinan)
    • (9) 
      Racemorphan (d, l-3-hydroxy-N-methylmorphinan)
    • but not including
    • (10) 
      Dextromethorphan (d-1,2,3,9,10,10a-hexahydro-6-methoxy-11-methyl-4H-10,4a-iminoethanophenanthren) and its salts
    • (11) 
      Dextrorphan (d-1,2,3,9,10,10a-hexahydro-11-methyl-4H-10,4a-iminoethanophenanthren-6-ol) and its salts
    • (12) 
      Levallorphan (l-11-allyl-1,2,3,9,10,10a-hexahydro-4H-10,4a-iminoethanophenanthren-6-ol) and its salts
    • (13) 
      Levargorphan (l-11-propargyl-1,2,3,9,10,10a-hexahydro-4H-10,4a-iminoethanophenanthren-6-ol) and its salts
    • (14) 
      Butorphanol (l-N-cyclobutylmethyl-3,14-dihydroxymorphinan) and its salts
    • (15) 
      Nalbuphine (N-cyclobutylmethyl-4,5-epoxy-morphinan-3,6,14-triol) and its salts
  • 11 
    Benzazocines, their salts, derivatives and salts of derivatives, including:
    • (1) 
      Phenazocine (1,2,3,4,5,6-hexahydro-6,11-dimethyl- 3-phenethyl-2,6-methano-3-benzazocin-8-ol)
    • (2) 
      Metazocine (1,2,3,4,5,6-hexahydro-3,6,11-trimethyl-2,6-methano-3-benzazocin-8-ol)
    • (3) 
      Pentazocine (1,2,3,4,5,6-hexahydro-6,11-dimethyl-3-(3-methyl-2-butenyl)-2,6-methano-3-benzazocin-8-ol)
    • but not including
    • (4) 
      Cyclazocine (1,2,3,4,5,6-hexahydro-6,11-dimethyl-3-(cyclopropylmethyl)-2,6-methano-3-benzazocin-8-ol) and its salts
  • 12 
    Ampromides, their salts, derivatives and salts of derivatives, including:
    • (1) 
      Diampromide (N-[2-(methylphenethylamino)propyl]propionanilide)
    • (2) 
      Phenampromide (N-(1-methyl-2-piperidino)ethyl)propionanilide)
    • (3) 
      Propiram (N-(1-methyl-2-piperidinoethyl)-N-2- pyridylpropionamide)
  • 13 
    Benzimidazoles, their salts, derivatives and salts of derivatives, including:
    • (1) 
      Clonitazene (2-(p-chlorobenzyl)-1-diethylaminoethyl-5-nitrobenzimidazole)
    • (2) 
      Etonitazene (2-(p-ethoxybenzyl)-1-diethylaminoethyl-5- nitrobenzimidazole)
  • 14 
    Phencyclidine (1-(1-phenylcyclohexyl)piperidine), its salts, derivatives and analogues and salts of derivatives and analogues, including:
    • (1) 
      Ketamine (2-(2-chlorophenyl)-2- (methylamino)cyclohexanone)
  • 15 
    Fentanyls, their salts, derivatives, and analogues and salts of derivatives and analogues, including:
    • (1) 
      Acetyl-α-methylfentanyl (N-[1-(α-methylphenethyl)-4-piperidyl]acetanilide)
    • (2) 
      Alfentanil (N-[1-[2-(4-ethyl-4,5-dihydro-5-oxo-1H-tetrazol-1-yl)ethyl]-4-(methoxymethyl)-4- piperidyl]propionanilide)
    • (3) 
      Carfentanil (methyl 4-[(1-oxopropyl)phenylamino]-1- (2-phenethyl)-4-piperidinecarboxylate)
    • (4) 
      p-Fluorofentanyl (4′ fluoro-N-(1-phenethyl-4-piperidyl) propionanilide)
    • (5) 
      Fentanyl (N-(1-phenethyl-4-piperidyl)propionanilide)
    • (6) 
      ß-Hydroxyfentanyl (N-[1-(ß-hydroxyphenethyl)-4- piperidyl] propionanilide)
    • (7) 
      ß-Hydroxy-3-methylfentanyl (N-[1(ß-hydroxyphenethyl)-3-methyl-4-piperidyl] propionanilide)
    • (8) 
      α-Methylfentanyl (N-[1-(α-methylphenethyl)-4- piperidyl] propionanilide)
    • (9) 
      α-Methylthiofentanyl (N-[1-[1-methyl-2-(2-thienyl)ethyl]-4-piperidyl] propionanilide)
    • (10) 
      3-Methylfentanyl (N-(3-methyl-1-phenethyl-4-piperidyl) propionanilide)
    • (11) 
      3-Methylthiofentanyl (N-[3-methyl-1-[2-(2-thienyl)ethyl]-4-piperidyl] propionanilide)
    • (11.1) 
      Remifentanil (dimethyl 4-carboxy-4-(N-phenylpropionamido)-1-piperidinepropionate)
    • (12) 
      Sufentanil (N-[4-(methoxymethyl)-1-[2-(2-thienyl)ethyl]-4- piperidyl] propionanilide)
    • (13) 
      Thiofentanyl (N-[1-[2-(2-thienyl)ethyl]-4-piperidyl] propionanilide)
    • (14) 
      4-Anilino-N-phenethylpiperidine (ANPP) (N-phenyl-1-(2-phenylethyl)piperidine-4-amine), its derivatives and analogues and salts of derivatives and analogues
  • 16 
    Tilidine (ethyl 2-(dimethylamino)-1-phenyl-3-cyclohexene-1-carboxylate), its salts, derivatives and salts of derivatives
  • 17 
    [Repealed, SOR/2018-147, s. 28]
  • 18 
    Synthetic cannabinoid receptor type 1 agonists, their salts, derivatives, isomers, and salts of derivatives and isomers, including those that fall within the following core chemical structure classes, with the exception of any substance that is identical to any phytocannabinoid and of ((3S)-2,3-dihydro-5-methyl-3-(4-morpholinylmethyl)pyrrolo[1,2,3-de]-1,4-benzoxazin-6-yl)-1-naphthalenyl-methanone (WIN 55,212-3) and its salts:
    • (1) 
      Any substance that has a 2-(cyclohexyl)phenol structure with substitution at the 1-position of the benzene ring by a hydroxy, ether or ester group and further substituted at the 5-position of the benzene ring, whether or not further substituted on the benzene ring to any extent, and substituted at the 3’-position of the cyclohexyl ring by an alkyl, carbonyl, hydroxyl, ether or ester, and whether or not further substituted on the cyclohexyl ring to any extent, including
      • (i) 
        Nabilone ((±)-trans-3-(1,1-dimethylheptyl)-6,6a,7,8,10,10a-hexahydro-1-hydroxy-6,6-dimethyl-9H-dibenzo[b,d]pyran-9-one)
      • (ii) 
        Parahexyl (3-hexyl-6,6,9-trimethyl-7,8,9,10-tetrahydro-6H-dibenzo[b,d]pyran-1-ol)
      • (iii) 
        3-(1,2-dimethylheptyl)-7,8,9,10-tetrahydro-6,6,9-trimethyl-6H-dibenzo[b,d]pyran-1-ol (DMHP)
      • (iv) 
        5-(1,1-dimethylheptyl)-2-(5-hydroxy-2-(3-hydroxypropyl)cyclohexyl)phenol (CP 55,940)
      • (v) 
        5-(1,1-dimethylheptyl)-2-(3-hydroxycyclohexyl)phenol (CP 47,497)
    • (2) 
      Any substance that has a 3-(1-naphthoyl)indole structure with substitution at the nitrogen atom of the indole ring, whether or not further substituted on the indole ring to any extent and whether or not substituted on the naphthyl ring to any extent, including
      • (i) 
        1-pentyl-3-(1-naphthoyl)indole (JWH-018)
      • (ii) 
        1-butyl-3-(1-naphthoyl)indole (JWH-073)
      • (iii) 
        1-pentyl-3-(4-methyl-1-naphthoyl)indole (JWH-122)
      • (iv) 
        1-hexyl-3-(1-naphthoyl)indole (JWH-019)
      • (v) 
        1-(4-pentenyl)-3-(1-naphthoyl)indole (JWH-022)
      • (vi) 
        1-butyl-3-(4-methoxy-1-naphthoyl)indole (JWH-080)
      • (vii) 
        1-pentyl-3-(4-methoxy-1-naphthoyl)indole (JWH-081)
      • (viii) 
        1-(2-morpholin-4-ylethyl)-3-(1-naphthoyl)indole (JWH-200)
      • (ix) 
        1-pentyl-3-(4-ethyl-1-naphthoyl)indole (JWH-210)
      • (x) 
        1-pentyl-3-(2-methoxy-1-naphthoyl)indole (JWH-267)
      • (xi) 
        1-[(N-methylpiperidin-2-yl)methyl]-3-(1-naphthoyl)indole (AM-1220)
      • (xii) 
        1-(5-fluoropentyl)-3-(1-naphthoyl)indole (AM-2201)
      • (xiii) 
        1-(5-fluoropentyl)-3-(4-methyl-1-naphthoyl)indole (MAM-2201)
      • (xiv) 
        1-(5-fluoropentyl)-3-(4-ethyl-1-naphthoyl)indole (EAM-2201)
      • (xv) 
        ((3R)-2,3-dihydro-5-methyl-3-(4-morpholinylmethyl)pyrrolo[1,2,3-de]-1,4-benzoxazin-6-yl)-1-naphthalenyl-methanone (WIN 55,212-2)
    • (3) 
      Any substance that has a 3-(1-naphthoyl)pyrrole structure with substitution at the nitrogen atom of the pyrrole ring, whether or not further substituted on the pyrrole ring to any extent and whether or not substituted on the naphthyl ring to any extent, including
      • (i) 
        1-pentyl-5-(2-fluorophenyl)-3-(1-naphthoyl)pyrrole (JWH-307)
    • (4) 
      Any substance that has a 3-phenylacetylindole structure with substitution at the nitrogen atom of the indole ring, whether or not further substituted on the indole ring to any extent and whether or not substituted on the phenyl ring to any extent, including
      • (i) 
        1-pentyl-3-(2-methoxyphenylacetyl)indole (JWH-250)
      • (ii) 
        1-pentyl-3-(2-methylphenylacetyl)indole (JWH-251)
      • (iii) 
        1-pentyl-3-(3-methoxyphenylacetyl)indole (JWH-302)
    • (5) 
      Any substance that has a 3-benzoylindole structure with substitution at the nitrogen atom of the indole ring, whether or not further substituted on the indole ring to any extent and whether or not substituted on the phenyl ring to any extent, including
      • (i) 
        1-(1-methylpiperidin-2-ylmethyl)-3-(2-iodobenzoyl)indole (AM-2233)
    • (6) 
      Any substance that has a 3-methanone(cyclopropyl)indole structure with substitution at the nitrogen atom of the indole ring, whether or not further substituted on the indole ring to any extent and whether or not substituted on the cyclopropyl ring to any extent, including
      • (i) 
        (1-pentyl-1H-indol-3-yl)(2,2,3,3-tetramethylcyclopropyl)-methanone (UR-144)
      • (ii) 
        (1-(5-fluoropentyl)-1H-indol-3-yl)(2,2,3,3-tetramethylcyclopropyl)-methanone (5F-UR-144)
      • (iii) 
        (1-(2-(4-morpholinyl)ethyl)-1H-indol-3-yl)(2,2,3,3-tetramethylcyclopropyl)-methanone (A-796,260)
    • (7) 
      Any substance that has a quinolin-8-yl 1H-indole-3-carboxylate structure with substitution at the nitrogen atom of the indole ring, whether or not further substituted on the indole ring to any extent and whether or not substituted on the quinolin-8-yl ring to any extent, including
      • (i) 
        1-pentyl-8-quinolinyl ester-1H-indole-3-carboxylic acid (PB-22)
      • (ii) 
        1-(5-fluoropentyl)-8-quinolinyl ester-1H-indole-3-carboxylic acid (5F-PB-22)
    • (8) 
      Any substance that has a 3-carboxamideindazole structure with substitution at the nitrogen atom of the indazole ring, whether or not further substituted on the indazole ring to any extent and whether or not substituted at the carboxamide group to any extent, including
      • (i) 
        N-(adamantan-1-yl)-1-pentyl-1H-indazole-3-carboxamide (AKB48)
      • (ii) 
        N-(adamantan-1-yl)-1-(5-fluoropentyl)-1H-indazole-3-carboxamide (5F-AKB48)
      • (iii) 
        N-(1-(aminocarbonyl)-2-methylpropyl)-1-(4-fluorobenzyl)-1H-indazole-3-carboxamide (AB-FUBINACA)
      • (iv) 
        N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-pentyl-1H-indazole-3-carboxamide (AB-PINACA)
    • (9) 
      Any substance that has a 3-carboxamideindole structure with substitution at the nitrogen atom of the indole ring, whether or not further substituted on the indole ring to any extent and whether or not substituted at the carboxamide group to any extent, including
      • (i) 
        N-(adamantan-1-yl)-1-fluoropentylindole-3-carboxamide (STS-135)
      • (ii) 
        N-(adamantan-1-yl)-1-pentylindole-3-carboxamide (APICA)
  • 18.1 
    Tapentadol (3-[(1R,2R)-3-(dimethylamino)-1-ethyl-2-methylpropyl]-phenol), its salts, derivatives and isomers and salts of derivatives and isomers
  • 19 
    Tramadol (2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol), its salts, isomers and salts of isomers and the following derivatives of tramadol and the salts, isomers and salts of isomers of those derivatives:
    • (1) 
      O-desmethyltramadol (3-[2-[(dimethylamino)methyl]-1-hydroxycyclohexyl]-phenol)
    • (2) 
      N,O-didesmethyltramadol (3-[1-hydroxy-2-[(methylamino)methyl]cyclohexyl]-phenol)
  • 20 
    AP-237 (1-(4-cinnamylpiperazin-1-yl)butan-1-one), its salts, derivatives and analogues and salts of derivatives and analogues, including:
    • (1) 
      2-methyl-AP-237 (1-(4-cinnamyl-2-methylpiperazin-1-yl)butan-1-one)
    • (2) 
      para-methyl-AP-237 ((E)-1-(4-(3-(p-tolyl)allyl)piperazin-1-yl)butan-1-one)
    • (3) 
      AP-238 (1-(4-cinnamyl-2,6-dimethylpiperazin-1-yl)propan-1-one)
  • SOR/97-227, s. 5
  • SOR/98-158, s. 1
  • SOR/99-372, ss. 1, 2
  • SOR/2000-244, s. 1(E)
  • SOR/2003-33, s. 1
  • SOR/2005-272, s. 1
  • SOR/2013-172, s. 9
  • SOR/2015-189, s. 1
  • SOR/2015-191, ss. 1, 2
  • SOR/2016-230, s. 279
  • SOR/2016-239, s. 8
  • SOR/2017-12, ss. 5 to 9
  • SOR/2017-276, s. 1
  • SOR/2018-69, ss. 72, 73, 74(F)
  • SOR/2018-147, s. 28
  • SOR/2019-120, s. 1
  • SOR/2019-169, s. 28
  • SOR/2021-43, s. 1
  • SOR/2024-99, s. 1
 

Date modified: